Vaccines To Cure Addictions?

This may be some of the more encouraging news in the faltering “war on drugs”:

Vaccines for addictive drugs work just like those for the flu: they trigger the immune system to produce antibodies that bind to the foreign substance and inactivate it. Molecules of cocaine, methamphetamine, nicotine, and other drugs are too small to spark an antibody response on their own, so scientists attach drug-like molecules to larger proteins that trigger formation of antibodies when injected into the blood. When a person takes a drug that he or she has been vaccinated against, antibodies bind to it and reduce the amount of drug that reaches the brain.

An addict who has been vaccinated might still fall off the wagon, but he or she wouldn’t get the rush of that next snort of cocaine or meth. Addiction experts say that thwarting the high should help prevent the person from spiraling back into regular use, allowing him or her to return to therapy or a treatment program much more quickly. “It could be comforting to know that even when you have dark moments and slip, you have the opportunity to get back on track,” says Michael Owens, a psychopharmacologist at the University of Arkansas for Medical Sciences, in Little Rock.

Long-awaited nicotine vaccines are likely to be the first available on doctors’ shelves. In initial clinical trials of smokers who were administered an experimental vaccine, a third of those given the highest dose quit, even though they were not asked to, versus 9 percent of those given placebos. A larger study of 200 patients has just concluded, with results expected in April.

Great. So pretty soon Kate Moss can legitimately wear a t-shirt proclaiming “I’ve shot up. Have you?”


4 Responses to “Vaccines To Cure Addictions?”
Comment by Boy Toy Subscribed to comments via email
2007-03-04 04:40:17

They will find a way to get their high off of something else unless they solve the underlying problem(s) in there life. Thank heavens I’m only addicted to loving and Diet Coke!

 
Comment by caltechgirl
2007-03-04 13:14:44

Actually, these will go NOWHERE, as they are somewhat biologically counterproductive. Cocaine, for example is active in the brain, and immune molecules don’t cross the blood brain barrier. Cocaine molecules do, though. Nicotine has a more somatic response, but it is also a part of several rather important metabolic functions in the body, so basically, I have no idea how they plan to make reliable vaccines that actually work without making the patient sick….

I suspect this is just bandwagoning on a “hot topic” for grant $$….

 
Comment by Young
2007-03-04 21:16:11

good idea, make rss here

 
Pingback by Judicious Asininity
2007-03-08 03:24:01

links from TechnoratiPerhaps science has a magic bulletElectric Venomnotes that scientists are developing vaccines for addictive drugs. Great news if it works out. Bad news for Afghani poppy farmers.

 

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